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NOT Open Access | Fenozyme Protects the Integrity of Blood Brain Barrier against Experimental Cerebral Malaria

November 7, 2019 - 20:48 -- NOT Open Access
Author(s): 
Zhao S, Duan H, Yang Y, Yan X, Fan K
Reference: 
Nano Lett. 2019 Nov 1 [Epub ahead of print]

Cerebral malaria is a lethal complication of malaria infection characterized by central nervous system dysfunction and is often not effectively treated by antimalarial combination therapies. It has been shown that the sequestration of the parasite-infected red blood cells that interact with cerebral vessel endothelial cells and the damage of the blood-brain barrier (BBB) play critical roles in the pathogenesis.

Medical Condition: 

A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle

November 5, 2019 - 12:43 -- Open Access
Author(s): 
Marta Tibúrcio, Annie S. P. Yang, Moritz Treeck, et al.
Reference: 
mBio September/October 2019 10:e01170-19

Plasmodium falciparum has a complex life cycle that involves interaction with multiple tissues inside the human and mosquito hosts. Identification of essential genes at all different stages of the P. falciparum life cycle is urgently required for clinical development of tools for malaria control and eradication.

Medical Condition: 

The Fever - a film by Katharina Weingartner

November 5, 2019 - 12:42 -- Malaria World
Tags: 

The Fever portrays the fight against malaria as a case study--in greed and courage. For The Fever Katharina Weingartner focuses on the complex history, present and future of malaria and observes the search for a solution. Could millions of deaths have been prevented, if ancient medical knowledge had been taken more seriously?

Podcast: Researchers Image Mode of Action of Quinoline Drug Class

November 1, 2019 - 10:01 -- Malaria Minute

Malaria Minute, 1 November 2019

Researchers image the mode of action of quinoline drugs, the function of rhomboid proteases is dynamically detailed and the WHO declares that 7 million cases of malaria have been reported in Burundi this year.

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New from MESA: Meet the MESA Correspondents that will cover the Keystone Symposia conference "The Malaria Endgame"

October 29, 2019 - 10:42 -- MESA Alliance

The MESA Correspondent volunteers report on the latest in malaria research from conferences around the world. The synopses are shared online, enabling people who could not attend the meeting to read about the latest advances. The MESA Correspondents Program is a collaboration between MESA and the conference organizers.

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