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Open Access | Invited Speaker Presentation: Transporters used by parasites as drug targets: tempting but underexploited

November 3, 2010 - 13:37 -- Patrick Sampao
Henry Staines
Malaria Journal 2010, 9(Suppl 2):I9 (20 October 2010)

Here are presented recent studies on this potential antimalarial target, utilising the rodent P. berghei model to investigate the physiological importance of D-glucose transport in transmission and liver life cycle stages and to generate an in vivo model for testing inhibitors of PfHT.

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Review: Exploiting the therapeutic potential of Plasmodium falciparum solute transporters

May 31, 2010 - 14:25 -- Patrick Sampao
Henry M. Staines, Elvira T. Derbyshire, Ksenija Slavic, Amanda Tattersall, Henri Vial, Sanjeev Krishna
Trends in Parasitology, Volume 26, Issue 6, June 2010, Pages 284-296

Presented here is an overview of our current understanding of the transport processes used by Plasmodium parasites, with an emphasis on their therapeutic potential.

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