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chabaudi

Open Access | Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene

May 24, 2010 - 13:18 -- Kabogo Ndegwa
Author(s): 
Afonso A, Neto Z, Castro H, Lopes D, Alves AC, Tomas AM, Rosario VD
Reference: 
Malaria Journal 2010, 9:135 (21 May 2010)

A mutation was found on the P. chabaudi cytb gene from the AS-ATQ sample a substitution at the residue Tyr268 for an Asn, this mutation is homologous to the one found in P. falciparum isolates resistant to ATQ.

Medical Treatment: 
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