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Short Communication: Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain

May 17, 2010 - 09:38 -- Kabogo Ndegwa
Roberta Ettari, Maria Zappalà, Nicola Micale, Tanja Schirmeister, Christoph Gelhaus, Matthias Leippe, Astrid Evers, Silvana Grasso
European Journal of Medicinal Chemistry, Volume 45, Issue 7, July 2010, Pages 3228-3233

This paper describes the synthesis of novel peptidomimetics bearing a protected aspartyl aldeyde warhead leading to the thioacylals 2a,b and the acylals 3a,b.

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