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Open Access | Phylogenomic analyses of malaria parasites and evolution of their exported proteins

June 16, 2011 - 08:33 -- Patrick Sampao
Christian Pick, Ingo Ebersberger, Tobias Spielmann , Iris Bruchhaus and Thorsten Burmester
BMC Evolutionary Biology 2011, 11:167

Our phylogenomic analyses strongly support the hypotheses that the Laverania have been founded by a single Plasmodium species switching from birds to African great apes or vice versa.

Medical Condition: 

Short communication: Target proteins of the cytosolic thioredoxin in Plasmodium falciparum

May 5, 2010 - 08:55 -- Patrick Sampao
Shin-ichiro Kawazu, Hitoshi Takemae, Kanako Komaki-Yasuda, Shigeyuki Kano
Parasitology International, Volume 59, Issue 2, June 2010, Pages 298-302

We captured 4 enzymes in the glycolysis pathway (hexokinase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), phosphoglycerate mutase and l-lactate dehydrogenase (LDH)) as Trx-targets, and we found that PfTrx-1 enhanced the activity of PfGAPDH and PfLDH.

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