The malarial CDK Pfmrk and its effector PfMAT1 phosphorylate DNA replication proteins and co-localize in the nucleus
Reference:
Molecular and Biochemical Parasitology, Volume 172, Issue 1, July 2010, Pages 9-18
We demonstrate that that these two proteins are substrates of Pfmrk-mediated phosphorylation and that PfMAT1 confers substrate specificity to the Pfmrk kinase complex.
Medical Condition: