Clinical trial of the use of chloroquine for monoinfections of P.falciparum and P. vivax. Although a small study and almost 7 years old, the data provide clear evidence of high grade chloroquine resistance in western Indonesia, a long distance from the known hot spot on the Island of Papua.
Both RDTs were highly sensitive, met WHO standards for the detection of falciparum malaria monoinfections where parasitaemia was >100 parasites/mul and were easy to use. CareStartTM persistent false positivity decreased quickly after successful anti-malarial treatment, making it a good choice for a RDT for a hyperendemic falciparum malaria area.
Vitamin A (retinol)-deficiency and falciparum malaria are two major public health problems in developing countries. Falciparum malaria is associated with significant destruction of erythrocytes and can lead to severe anaemia.