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Review: IgM, FcµRs, and Malarial Immune Evasion

April 22, 2010 - 12:03 -- Kabogo Ndegwa
Daniel M. Czajkowsky, Ali Salanti, Sisse B. Ditlev, Zhifeng Shao, Ashfaq Ghumra, J. Alexandra Rowe, and Richard J. Pleass
J. Immunol., May 2010; 184: 4597 – 4603

IgM is an ancestral Ab class found in all jawed vertebrates, from sharks to mammals. This ancient ancestry is shared by malaria parasites (genus Plasmodium) that infect all classes of terrestrial vertebrates with whom they coevolved.

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