The authors suggest that parasite DNA complexed with protein is the main trigger for activation of DCs in malaria-infected red blood cells.
Future Microbiology August 2010, Vol. 5, No. 8, Pages 1167-1171
The Journal of Immunology, 2010, Volume 184, Issue 8 Pages 4338 -4348
Dendritic cells (DCs) play a crucial role in the development of protective immunity to malaria. However, it remains unclear how malaria parasites trigger immune responses in DCs.