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anti-malarials

Open Access | The ACTwatch project: methods to describe anti-malarial markets in seven countries

November 2, 2011 - 09:25 -- Kabogo Ndegwa
Author(s): 
Shewchuk T, O'Connell KA, Goodman C, Hanson K, Chapman S, Chavasse D
Reference: 
Malaria Journal 2011, 10:325 (31 October 2011)

MalariaWorldACT watch is a unique multi-country research project that threads together anti-malarial supply and consumer behaviour to provide an evidence base to policy makers that can help determine where interventions may positively impact access to and use of quality-assured ACT and RDTs.

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Open Access | Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression

August 26, 2010 - 14:37 -- Kabogo Ndegwa
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Author(s): 
Maria Isabel Veiga, Pedro Eduardo Ferreira, Berit Aydin Schmidt, Ulf Ribacke, Anders Björkman, Ales Tichopad, José Pedro Gil
Reference: 
PLoS ONE 5(8): e12408

Both cell cycle delay and induced gene expression represent potentially important mechanisms for parasites to escape the effect of the antimalarial drug.

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Open Access | Research: How can malaria rapid diagnostic tests achieve their potential? A qualitative study of a trial at health facilities in Ghana

April 16, 2010 - 08:03 -- Kabogo Ndegwa
Author(s): 
Chandler CI, Whitty CJ, Ansah EK
Reference: 
Malaria Journal 2010, 9:95 (14 April 2010)

Rapid diagnostic tests (RDTs) for malaria are at the early stages of introduction across malaria endemic countries. This is central to efforts to decrease malaria overdiagnosis and the consequent overuse of valuable anti-malarials and underdiagnosis of alternative causes of fever.

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