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sulfadoxine resistance

Open Access | Origin and Evolution of Sulfadoxine Resistant Plasmodium falciparum

April 8, 2010 - 07:48 -- Kabogo Ndegwa
S Vinayak, MT Alam, T Mixson-Hayden, AM McCollum, R Sem, NK Shah, P Lim, S Muth, WO Rogers, T Fandeur, JW Barnwell, AA Escalante, C Wongsrichanalai, F Ariey, SR Meshnick, V Udhayakumar
PLoS Pathog (2010) 6: e1000830

The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa.

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