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neglected pathogens

Open Access | A Systems-Based Analysis of Plasmodium vivax Lifecycle Transcription from Human to Mosquito

April 7, 2010 - 12:16 -- Kabogo Ndegwa
Scott J. Westenberger, Colleen M. McClean, Rana Chattopadhyay, Neekesh V. Dharia, Jane M. Carlton, John W. Barnwell, William E. Collins, Stephen L. Hoffman, Yingyao Zhou, Joseph M. Vinetz, Elizabeth A. Winzeler
PLoS Negl Trop Dis 4(4): e653


To overcome the barriers to traditional molecular biology in P. vivax, we examined parasite transcriptional changes in samples from infected patients and mosquitoes in order to characterize gene function, define regulatory sequences and reveal new potential vaccine candidate genes.

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