Severe malaria anemia is characterized by inhibited/altered erythropoiesis and presence of hemozoin-(HZ)-laden bone-marrow macrophages.
Blood, 18 November 2010, Vol. 116, No. 20, pp. 4328-4337
Blood, 25 March 2010, Vol. 115, No. 12, pp. 2500-2507
Our present studies suggest that PfPI3K, a novel phosphatidylinositol-3-kinase (PI3K) in Plasmodium falciparum, is exported to the host erythrocyte by the parasite in an active form.