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Anopheles

Open Access | Activation of Akt Signaling Reduces the Prevalence and Intensity of Malaria Parasite Infection and Lifespan in Anopheles stephensi Mosquitoes

August 2, 2010 - 14:08 -- Patrick Sampao
Author(s): 
Vanessa C., Anna Drexler., et al.
Reference: 
PLoS Pathog 6(7): e1001003

Here, we demonstrate that increased Akt signaling in the mosquito midgut disrupts parasite development and concurrently reduces the duration that mosquitoes are infective to humans.

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Open Access | Knockdown resistance in Anopheles vagus, An. sinensis, An. paraliae and An. peditaeniatus populations of the Mekong region

July 26, 2010 - 08:13 -- Patrick Sampao
Author(s): 
Katrijn Verhaeghen , Wim Van Bortel , Ho Dinh Trung, Tho Sochantha , Kalouna Keokenchanh and Marc Coosemans
Reference: 
Parasites & Vectors 2010, 3:59

In this study, the resistance status of the potential malaria vectors An. vagus, An. sinensis, An. paraliae and An. peditaeniatus was assessed.

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Human Antibody Response to Anopheles gambiae Saliva: An Immuno-Epidemiological Biomarker to Evaluate the Efficacy of Insecticide-Treated Nets in Malaria Vector Control

July 5, 2010 - 07:07 -- Patrick Sampao
Author(s): 
Papa M., Anne P., et al.
Reference: 
Am J Trop Med Hyg, Jul 2010; 83: 115 - 121.

This study investigates a potential immunological marker, based on human antibody responses to Anopheles saliva, as a new indicator to evaluate the efficacy of insecticide-treated nets (ITNs).

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Microgeographic Genetic Variation of the Malaria Vector Anopheles darlingi Root (Diptera: Culicidae) from Córdoba and Antioquia, Colombia

July 2, 2010 - 13:16 -- Patrick Sampao
Author(s): 
Lina A. Gutiérrez, Giovan F. Gómez, John J. González, Martha I. Castro, Shirley Luckhart, Jan E. Conn, AND Margarita M. Correa
Reference: 
Am J Trop Med Hyg, Jul 2010; 83: 38 - 47.

This study was conducted to test genetic variation of An. darlingi at a microgeographic scale (approximately 100 km) from localities in Córdoba and Antioquia states, in western Colombia, to better understand the potential contribution of population genetics to local malaria control programs.

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Phylogenetic inference of Indian malaria vectors from multilocus DNA sequences

June 30, 2010 - 13:52 -- Patrick Sampao
Author(s): 
Jyotsana Dixit, Hemlata Srivastava, Meenu Sharma, Manoj K. Das, O.P. Singh, K. Raghavendra, Nutan Nanda, Aditya P. Dash, D.N. Saksena, Aparup Das
Reference: 
Infection, Genetics and Evolution, Volume 10, Issue 6, August 2010, Pages 755-763

Multilocus molecular phylogenetic study of Indian anophelines and An. gambiae was conducted at each individual genetic region using Neighbour Joining (NJ), Maximum Likelihood (ML), Maximum Parsimony (MP) and Bayesian approaches.

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Open Access | Distribution of ace-1R and resistance to carbamates and organophosphates in Anopheles gambiae s.s. populations from Cote d'Ivoire

June 18, 2010 - 12:19 -- Patrick Sampao
Author(s): 
Ahoua Alou LP, Koffi AA, Adja MA, Tia E, Kouassi PK, Kone M, Chandre F
Reference: 
Malaria Journal 2010, 9:167 (16 June 2010)

This study revealed a wide distribution of insensitive acetylcholinesterase due to the G119S mutation in both M and S molecular forms of the populations of An. gambiae s.s. tested.

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Open Access | Pyrethroid resistance in Anopheles gambiae leads to increased susceptibility to the entomopathogenic fungi Metarhizium anisopliae and Beauveria bassiana

June 18, 2010 - 12:11 -- Patrick Sampao
Author(s): 
Howard AF, Koenraadt CJ, Farenhorst M, Knols BG, Takken W
Reference: 
Malaria Journal 2010, 9:168 (16 June 2010)

The insecticide-resistant mosquito strain was susceptible to both species of fungus indicating that entomopathogenic fungi can be used in resistance management and integrated vector management programmes to target insecticide-resistant mosquitoes.

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Open Access | Is aging raw cattle urine efficient for sampling Anopheles arabiensis Patton?

June 16, 2010 - 11:46 -- Patrick Sampao
Author(s): 
Aneth M., Beda J., et al.
Reference: 
BMC Infectious Diseases 2010, 10:172

A total of 7871 mosquitoes were collected throughout the study period. 49.8% of the mosquitoes were collected from resting box treated with urine daily; 21.6% and 20.0% were from boxes treated 3 and 7 days respectively. Only 8.6% were from untreated resting box (control). The proportion collected indoors was ~2 folds greater than the outdoor. Of all mosquitoes, 12.3% were unfed, 4.1% full fed, 34.2% semi-gravid and 49.4% gravid.

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Open Access | Cloning, expression and transmission-blocking activity of anti-PvWARP, malaria vaccine candidate, in Anopheles stephensi mysorensis

June 14, 2010 - 14:13 -- Kabogo Ndegwa
Author(s): 
Gholizadeh S, Basseri H, Zakeri S, Ladoni H, Djadid N
Reference: 
Malaria Journal 2010, 9:158 (11 June 2010)

This is the first report on P. vivax WARP expression in E. coli providing an essential base for development of the malaria TBV against P. vivax. This may greatly assist in malaria elimination, especially in the oriental corner of WHO Eastern Mediterranean Regional Office (WHO/EMRO), including Afghanistan, Iran and Pakistan.

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Open Access | Identification of three single nucleotide polymorphisms in Anopheles gambiae immune signaling genes that are associated with natural Plasmodium falciparum infection

June 14, 2010 - 13:00 -- Kabogo Ndegwa
Author(s): 
Horton AA, Lee Y, Coulibaly CA, Rashbrook VK, Cornel AJ, Lanzaro GC, Luckhart S
Reference: 
Malaria Journal 2010, 9:160 (11 June 2010)

Seven of these eight infection-associated and linked SNPs alter codon frequency or introduce non-synonymous changes that would be predicted to alter protein structure and, hence, function, suggesting that these SNPs could alter immune signaling and responsiveness to parasite infection.

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