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gametocytogenesis

Protein export marks the early phase of gametocytogenesis of the human malaria parasite plasmodium falciparum

March 25, 2010 - 13:54 -- Ingeborg van Schayk
Author(s): 
Francesco Silvestrini, Edwin Lasonder, Anna Olivieri, Grazia Camarda, Ben van Schaijk, Massimo Sanchez, Sumera Younis Younis, Robert Sauerwein, and Pietro Alano
Reference: 
Mol. Cell. Proteomics. published 22 March 2010, 10.1074/mcp.M900479-MCP200

This work indicates that protein export profoundly marks early sexual differentiation in P. falciparum, probably contributing to host cell remodelling in this phase of the life cycle, and that gametocyte-enriched molecules are recruited to modulate this process in gametocytogenesis.

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