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murine malaria

Age-Dependent Sex Bias in Clinical Malarial Disease in Hypoendemic Regions

May 30, 2012 - 06:15 -- Kabogo Ndegwa
Pathak S, Rege M, Gogtay NJ, Aigal U, Sharma SK, et al
PLoS ONE 7(4): e35592

MalariaWorldThis study demonstrates an age-dependent sex bias in clinical malaria in hypoendemic regions and enhanced incidence of clinical malaria in males following puberty.

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NOT Open Access | The Aminopeptidase Inhibitor CHR-2863 Is an Orally Bioavailable Inhibitor of Murine Malaria

May 15, 2012 - 14:29 -- Kabogo Ndegwa
Tina S. Skinner-Adams, Christopher L. Peatey, Donald L. Gardiner, et al.
Antimicrob. Agents Chemother. June 2012 vol. 56 no. 6 3244-3249

MalariaWorldMalaria remains a significant risk in many areas of the world, with resistance to the current antimalarial pharmacopeia an ever-increasing problem.

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Open Access | Murine malaria is associated with significant hearing impairment

June 14, 2010 - 13:10 -- Kabogo Ndegwa
Schmutzhard J, Kositz CH, Lackner P, Dietmann A, Fischer M, Glueckert R, Reindl M, Stephan K, Riechelmann H, Schrott-Fischer A, Schmutzhard E
Malaria Journal 2010, 9:159 (11 June 2010)

Plasmodium falciparum malaria has been suspected to cause hearing loss. Developmental, cognitive and language disorders have been observed in children, surviving cerebral malaria.


Open Access | Beneficial effect of aurothiomalate on murine malaria

May 10, 2010 - 08:56 -- Kabogo Ndegwa
Alesutan I, Bobbala D, Qadri SM, Estremera A, Foller M, Lang F
Malaria Journal 2010, 9:118 (7 May 2010)

Sodium aurothiomalate influences the survival of Plasmodium berghei-infected mice, an effect only partially explained by stimulation of eryptosis.

Open Access | Up- and down-modulation of liver cytochrome P450 activities and associated events in two murine malaria models

March 23, 2010 - 21:06 -- Ingeborg van Schayk
Ana Cecilia AX De-Oliveira, Renato S Carvalho, Flavio HM Paixao, Hellen S Tavares, Luciana S Gueiros, Carolina M Siqueira, Francisco JR Paumgartten
Malaria Journal 2010, 9:81 (22 March 2010)

This study was undertaken to evaluate the time course of CYP alterations in lethal (Plasmodium berghei ANKA) and non-lethal (Plasmodium chabaudi chabaudi) murine malaria.

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