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Loss of Ability To Self-Heal Malaria upon Taurine Transporter Deletion

March 21, 2010 - 11:18 -- Ingeborg van Schayk
Denis Delic, Ulrich Warskulat, Elena Borsch, Saad Al-Qahtani, Saleh Al-Quraishi, Dieter Haussinger, and Frank Wunderlich
Infect. Immun. 2010;78 1642-1649

Deletion of the taurine transporter gene (taut) results in lowered levels of taurine, the most abundant amino acid in mammals. Here, we show that taut–/– mice have lost their ability to self-heal blood-stage infections with Plasmodium chabaudi malaria. 

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