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vivax

Open Access | Research: Active case detection, treatment of falciparum malaria with combined chloroquine and sulphadoxine/pyrimethamine and vivax malaria with chloroquine and molecular markers of anti-malarial resistance in the Republic of Vanuatu

April 7, 2010 - 12:38 -- Kabogo Ndegwa
Author(s): 
Kinzer MH, Chand K, Basri H, Lederman ER, Susanti AI, Elyazar I, Taleo G, Rogers WO, Bangs MJ, Maguire JD
Reference: 
Malaria Journal 2010, 9:89 (6 April 2010)

The only in vivo malaria drug efficacy trial thus far published from the Republic of Vanuatu showed chloroquine/sulphadoxine-pyrimethamine combination therapy for P. falciparum and chloroquine alone for P. vivax to be highly efficacious.

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Bottleneck effects on vaccine-candidate antigen diversity of malaria parasites in Thailand

March 31, 2010 - 11:26 -- Patrick Sampao
Author(s): 
Somchai Jongwutiwes, Chaturong Putaporntip, Austin L. Hughes
Reference: 
Vaccine, Volume 28, Issue 18, 19 April 2010, Pages 3112-3117

These results suggest a two-pronged strategy for malaria eradication: (1) strenuous non-vaccine control measures that will cause a severe population bottleneck in the parasite; and (2) a subsequent local vaccine focused on one or a few locally occurring alleles at antigen-encoding loci.

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Open Access | Serologic Markers for Detecting Malaria in Areas of Low Endemicity, Somalia, 2008

March 24, 2010 - 10:41 -- Ingeborg van Schayk
Author(s): 
T. Bousema et al.
Reference: 
EID, Volume 16, Number 3–March 2010

Areas in which malaria is not highly endemic are suitable for malaria elimination, but assessing transmission is difficult because of lack of sensitivity of commonly used methods. We evaluated serologic markers for detecting variation in malaria exposure in Somalia.

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Open Access | Comparative detection of Plasmodium vivax and Plasmodium falciparum DNA in saliva and urine samples from symptomatic malaria patients in a low endemic area

March 14, 2010 - 10:17 -- Ingeborg van Schayk
Author(s): 
Pattakorn Buppan, Chaturong Putaporntip, Urassaya Pattanawong, Sunee Seethamchai, Somchai Jongwutiwes
Reference: 
Malaria Journal 2010, 9:72 (9 March 2010)

Saliva and urine samples could be alternative noninvasive sources of DNA for molecular detection of both P. falciparum and P. vivax. Further improvement of the detection method will offer an opportunity to use these samples for diagnosis of malaria.

Open Access | Assessing the future threat from vivax malaria in the United Kingdom using two markedly different modelling approaches

March 9, 2010 - 14:10 -- Ingeborg van Schayk
Author(s): 
Steven W Lindsay, David G Hole, Robert A Hutchinson, Shane A Richards, Steven G Willis
Reference: 
Malaria Journal 2010, 9:70 (5 March 2010)

Although the future climate in the UK is favourable for the transmission of vivax malaria, the future risk of locally transmitted malaria is considered low because of low vector biting rates and the low probability of vectors feeding on a malaria-infected person.

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Test characteristics of the SD FK80 Plasmodium falciparum/Plasmodium vivax malaria rapid diagnostic test in a non-endemic setting

November 26, 2009 - 12:29 -- Ingeborg van Schayk
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Author(s): 
Philippe Gillet, David PJ van Dijk, Emmanuel Bottieau, Lieselotte Cnops, Marjan Van Esbroeck, Jan Jacobs
Reference: 
Malaria Journal 2009, 8:262 (22 November 2009)

The SD FK80 P.f/P.v Malaria Antigen Rapid Test (Standard Diagnostics, Korea) (FK80) is a three-band malaria rapid diagnostic test detecting Plasmodium falciparum histidine-rich protein-2 (HRP-2) and Plasmodium vivax-specific lactate dehydrogenase (Pv-pLDH). The present study assessed its performance in a non-endemic setting.

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Mini review: A new global malaria eradication strategy: implications for malaria research from an Indian perspective

November 26, 2009 - 06:48 -- Kabogo Ndegwa
Author(s): 
Neeru Singh
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, December 2009, Pages 1202-1203, doi:10.1016/j.trstmh.2009.04.023

The Roll Back Malaria Partnership has developed the Global Malaria Action Plan for a substantial reduction in the burden of malaria and its eradication in the long term.

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Interaction of malaria with a common form of severe thalassemia in an Asian population

November 11, 2009 - 09:29 -- Ingeborg van Schayk
Author(s): 
A. O'Donnell, A. Premawardhena, M. Arambepola, R. Samaranayake, S. J. Allen, T. E. A. Peto, C. A. Fisher, J. Cook, P. H. Corran, Nancy F. Olivieri, and D. J. Weatherall
Reference: 
PNAS November 3, 2009 vol. 106 no. 44 18716-18721

Because the role of the environment in the course of severe thalassemia has been neglected completely and because malaria due to both Plasmodium falciparum and Plasmodium vivax has been prevalent in Sri Lanka, we carried out a pilot study of patients with HbE β thalassemia that showed high frequencies of antibodies to both parasite species and that 28.6% of the children had DNA-based evidence of current infection with P. vivax.

 

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Case report: Histopathology of Fatal Respiratory Distress Caused by Plasmodium vivax Malaria

November 10, 2009 - 21:20 -- Ingeborg van Schayk
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Author(s): 
Neena Valecha, Rock G. W. Pinto, Gareth D. H. Turner, Ashwani Kumar, Savio Rodrigues, Nagesh G. Dubhashi, Edmond Rodrigues, Sidhartha S. Banaulikar, Ruchi Singh, Aditya P. Dash, AND J. Kevin Baird
Reference: 
Am J Trop Med Hyg 2009;81 758-762

An otherwise healthy 20-year-old woman in Goa, India, received antibiotics after a diagnosis of upper respiratory tract infection. In this patient, vivax malaria caused a rapidly fatal respiratory distress.

 

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Case report: Successful Sporozoite Challenge Model in Human Volunteers with Plasmodium vivax Strain Derived from Human Donors

November 10, 2009 - 20:48 -- Ingeborg van Schayk
Author(s): 
Sócrates Herrera, Olga Fernández, María R. Manzano, Bermans Murrain, Juana Vergara, Pedro Blanco, Ricardo Palacios, Juan D. Vélez, Judith E. Epstein, Mario Chen-Mok, Zarifah H. Reed, AND Myriam Arévalo-Herrera
Reference: 
Am J Trop Med Hyg 2009;81 740-746

In conclusion, malaria-naive volunteers can be safely and reproducibly infected with bites of 2–10 An. albimanus mosquitoes carrying P. vivax sporozoites. This challenge method is suitable for vaccine and anti-malarial drug testing.

 

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