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nucleoside transporter 1

Subpatent infection with nucleoside transporter 1-deficient Plasmodium blood stage parasites confers sterile protection against lethal malaria in mice

March 15, 2010 - 13:55 -- Ingeborg van Schayk
Author(s): 
Ahmed S. I. Aly, Megan J. Downie, Choukri Ben Mamoun and Stefan H. I. Kappe
Reference: 
Cellular Microbiology Early View

The study demonstrates that genetic manipulation provides a platform for the designed, complete attenuation of malaria parasite blood stages and suggests testing the safety and efficacy of P. falciparum NT1 knockout strains in humans.

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