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malaria pigment hemozoin

Malaria hemozoin modulates susceptibility of immature monocyte-derived dendritic cells to HIV-1 infection by inducing a mature-like phenotype

March 15, 2010 - 11:18 -- Ingeborg van Schayk
Author(s): 
Juliette Diou, Mélanie R. Tardif, Corinne Barat and Michel J. Tremblay
Reference: 
Cellular Microbiology, Early View

There is still limited information about the putative impact of the malaria pigment hemozoin (HZ) on the dissemination of HIV-1. As so, we propose a premise where HZ present in human dendritic cells (DCs) could modulate HIV-1 transfer to CD4+ T cells. 

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