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pfcrt alleles

Open Access | Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum

March 14, 2010 - 10:30 -- Ingeborg van Schayk
Nahla B Gadalla, Salah Eldin Elzaki, Ebtihal Mukhtar, David C Warhurst, Badria El-Sayed, Colin J Sutherland
Malaria Journal 2010, 9:74 (12 March 2010)

Parasite resistance to the anti-malarial drug chloroquine is common in eastern Sudan. Dynamic within-host changes in the relative abundance of both sensitive and resistant Plasmodium falciparum parasites were examined in a cohort of chloroquine-treated patients presenting with uncomplicated falciparum malaria, using a novel allele-specific quantitative approach.

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