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mosquitoes

Open Access | Interferon-gamma, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

February 10, 2011 - 11:27 -- Kabogo Ndegwa
Author(s): 
Perlaza B, Sauzet J, Brahimi K, BenMohamed L, Druilhe P
Reference: 
Malaria Journal 2011, 10:27 (8 February 2011)

Immunity against the pre-erythrocytic stages of malaria is the most promising, as it is strong and fully sterilizing.

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Open Access | Identification of a fibrinogen-related protein (FBN9) gene in neotropical anopheline mosquitoes

February 9, 2011 - 07:04 -- Kabogo Ndegwa
Author(s): 
Oliveira SB, Ibraim IC, Tadei WP, Ruiz JC, Nahum LA, Brito CF, Moreira LA
Reference: 
Malaria Journal 2011, 10:21 (2 February 2011)

The present work adds new insights into the conserved role of fbn9 in insect immunity in a broader range of anopheline species and reinforces the possibility of manipulating mosquito immunity to design novel pathogen control strategies.

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Open Access | Arbovirus Prevalence in Mosquitoes, Kenya

February 4, 2011 - 08:19 -- Patrick Sampao
Author(s): 
A. Desiree LaBeaud, Laura J. Sutherland,Samuel Muiruri, Eric M. Muchiri, Laurie R. Gray, Peter A. Zimmerman, Amy G. Hise, and Charles H. King
Reference: 
Emerging Infectious Diseases, Volume 17, Number 2–February 2011

Our data demonstrate the local abundance of mosquitoes that could propagate arboviral infections in Kenya and the high prevalence of vector arbovirus positivity during a Rift Valley fever outbreak.

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Review : Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?

February 2, 2011 - 12:47 -- Patrick Sampao
Author(s): 
Hilary Ranson, Raphael N’Guessan, Jonathan Lines, Nicolas Moiroux, Zinga Nkuni, Vincent Corbel
Reference: 
Trends in Parasitology, Volume 27, Issue 2, February 2011, Pages 91-98

As we move into the malaria eradication era, it is vital that the implications of insecticide resistance are understood and strategies to mitigate these effects are implemented.

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Infection of Anopheles gambiae mosquitoes with entomopathogenic fungi: effect of host age and blood-feeding status

January 28, 2011 - 08:47 -- Kabogo Ndegwa
Author(s): 
Ladslaus L. Mnyone, Matthew J. Kirby, Monica W. Mpingwa, Dickson W. Lwetoijera, Bart G. J. Knols, Willem Takken, Constantianus J. M. Koenraadt & Tanya L. Russell
Reference: 
Parasitology Research, Volume 108, Number 2, 317-322

Physiological characteristics of insects can influence their susceptibility to fungal infection of which age and nutritional status are among the most important.

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Open Access | Clusters of Temporal Discordances Reveal Distinct Embryonic Patterning Mechanisms in Drosophila and Anopheles

January 27, 2011 - 06:49 -- Kabogo Ndegwa
Author(s): 
Dmitri Papatsenko, Michael Levine, Yury Goltsev
Reference: 
PLoS Biol 9(1): e1000584

Evolutionary innovations can be driven by spatial and temporal changes in gene expression. Several such differences have been documented in the embryos of lower and higher Diptera.

Open Access | Possible impact of rising sea levels on vector-borne infectious diseases

January 25, 2011 - 08:10 -- Kabogo Ndegwa
Author(s): 
Ranjan Ramasamy, Sinnathamby N
Reference: 
BMC Infectious Diseases 2011, 11:18

Vector-borne infectious diseases (VBD) are a significant cause of morbidity and mortality in humans and animals.

Open Access | Plasmodium falciparum liver stage antigen-1 is cross-linked by tissue transglutaminase

January 25, 2011 - 06:51 -- Kabogo Ndegwa
Author(s): 
Nicoll WS, Sacci JB, Rudolfo C, Di Giacomo G, Piacentini M, Holland ZJ, Doerig C, Hollingdale MR, Lanar DE
Reference: 
Malaria Journal 2011, 10:14 (21 January 2011)

While the role of LSA-1 is still unknown these results suggest that it becomes highly cross-linked which may aid in the protection of the parasite as it develops.

The role of Pvs28 in sporozoite development in Anopheles sinensis and its longevity in BALB/c mice

January 20, 2011 - 11:35 -- Kabogo Ndegwa
Author(s): 
Tong-Soo Kim, Hyung-Hwan Kim, Sung-Ung Moon, Sun-Sim Lee, E-Hyun Shin, Chang-Mi Oh, Yoon-Joong Kang, Do-Kyung Kim, Youngjoo Sohn, Hyuck Kim, Hyeong-Woo Lee
Reference: 
Experimental Parasitology, Volume 127, Issue 2, February 2011, Pages 346-350

To develop a vivax malaria vaccine for blocking malarial transmission, the ookinete surface protein Pvs28 was cloned from Korean malaria patients using polymerase chain reaction.

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Open Access | Global response of Plasmodium falciparum to hyperoxia: a combined transcriptomic and proteomic approach

January 13, 2011 - 07:58 -- Kabogo Ndegwa
Author(s): 
Torrentino-Madamet M, Almeras L, Desplans J, Le Priol Y, Belghazi M, Pophillat M, Fourquet P, Jammes Y, Parzy D
Reference: 
Malaria Journal 2011, 10:4 (11 January 2011)

These results seem to indicate that hyperoxia activates antioxidant defence systems in parasites to preserve the integrity of its cellular structures.

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