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transmission

Open Access | Climatic variables and malaria transmission dynamics in Jimma town, south west Ethiopia

March 7, 2011 - 09:18 -- Patrick Sampao
Author(s): 
Alemu A, Abebe G, Tsegaye W, Golassa L
Reference: 
Parasites & Vectors 2011, 4:30 (2 March 2011)

Time-series analysis was conducted using data on monthly meteorological variables and monthly total malaria in Jimma town, south west Ethiopia, for the period 2000-2009. All the data were entered and analyzed using SPSS-15 database program.

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Configurational Entropy Reallocation and Complex Loop Dynamics of the Mosquito-Stage Pvs25 Protein Complexed with the Fab Fragment of the Malaria Transmission Blocking Antibody 2A8

January 6, 2011 - 14:36 -- Patrick Sampao
Author(s): 
Athanassios Stavrakoudis and Ioannis G. Tsoulos
Reference: 
J. Chem. Theory Comput, December 29, 2010

This trend in entropy redistribution was found to be in direct relationship with specific interactions with the antibody’s binding site. Results from root-mean-square fluctuations/deviations and dihedral angle principal component analysis further support this finding.

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Opinion: Consideration of ethics in primaquine therapy against malaria transmission

December 31, 2010 - 14:34 -- Patrick Sampao
Author(s): 
J. Kevin Baird, Claudia Surjadjaja
Reference: 
Trends in Parasitology, Volume 27, Issue 1, January 2011, Pages 11-16

Clinical studies in the 1950s demonstrated gametocytocidal primaquine to be safe without G6PDd screening. However, the evaluated G6PDd variant, African A-, represents mild sensitivity to primaquine.

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Open Access | The impact of the expansion of urban vegetable farming on malaria transmission in major cities of Benin

December 14, 2010 - 08:28 -- Patrick Sampao
Author(s): 
Yadouleton A, Raphael N, Hyacinthe A, Asidi A, Michel B, Razack O, Gil P, Gazard K, Martin A
Reference: 
Parasites & Vectors 2010, 3:118 (12 December 2010)

These findings showed that communities living close to vegetable farms are permanently exposed to malaria throughout the year, whereas the risk in those living far from such agricultural practices is limited and only critical during the rainy seasons.

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Is parasite clearance clinically important after malaria treatment in a high transmission area? A 3-month follow-up of home-based management with herbal medicine or ACT

December 9, 2010 - 12:13 -- Patrick Sampao
Author(s): 
Merlin L. Willcox, Bertrand Graz, Chiaka Diakite, Jacques Falquet, Florent Dackouo, Oumar Sidibe, Sergio Giani, Drissa Diallo
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 105, Issue 1, January 2011, Pages 23-31

This study, in a high transmission area of South Mali, explores whether residual parasitaemia at day 28 was associated with subsequent malaria episodes and/or anaemia.

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Towards eradication: three years after the tsunami of 2004, has malaria transmission been eliminated from the island of Simeulue?

November 15, 2010 - 14:07 -- Patrick Sampao
Author(s): 
Mohammad Sudomo, Yusniar Arianti, Isra Wahid, Din Safruddin, Erling M. Pedersen, J. Derek Charlwood
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 104, Issue 12, December 2010, Pages 777-781

The results indicate that despite the continuing presence of potential vectors in some places the anti-malaria measures introduced following the tsunami have controlled, and may be close to eliminating, malaria from the island.

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Open Access | Oral Presentation: Impact of protective haemoglobins C and S on P. falciparum malaria transmission in endemic area

November 8, 2010 - 09:46 -- Patrick Sampao
Author(s): 
Louis C Gouagna, Germana Bancone, Frank Yao, Carlo Costantini, Jean-Bosco Ouedraogo, David Modiano
Reference: 
Malaria Journal 2010, 9(Suppl 2):O17 (20 October 2010)

With regard to malaria, a major selective force in recent human evolution, protective erythrocyte variants have been describe, but little is known as to their possible impact on the transmission of the parasite from the human host to the Anopheles vector.

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Open Access | Oral Presentation: Predicted impact of mosquito-stage transmission-blocking vaccines using an ensemble of microsimulations

November 5, 2010 - 14:46 -- Patrick Sampao
Author(s): 
Aurelio Di Pasquale, Nicolas Maire, Thomas Smith
Reference: 
Malaria Journal 2010, 9(Suppl 2):O11 (20 October 2010)

The outputs of the stochastic individual-based simulations are predictions of the epidemiological impact and comparative cost-effectiveness of conceivable control measures, alone or in combination.

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Open Access | Oral Presentation: Modeling the effects of vector control interventions in reducing malaria transmission, morbidity and mortality

November 5, 2010 - 11:15 -- Patrick Sampao
Author(s): 
Nakul Chitnis, Diggory Hardy, Guillaume Gnaegi, Konstantina Boutsika, Nicolas Maire, Richard Steketee, Allan Schapira, Tom Smith
Reference: 
Malaria Journal 2010, 9(Suppl 2):O7 (20 October 2010)

We use numerical simulation of mathematical models of malaria in humans and mosquitoes to provide robust quantitative predictions of effectiveness of different strategies in reducing transmission, morbidity and mortality.

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A Novel Histological Grading Scheme for Placental Malaria Applied in Areas of High and Low Malaria Transmission

October 15, 2010 - 13:58 -- Patrick Sampao
Author(s): 
Atis Muehlenbachs,Michal Fried,Rose McGready,Whitney E. Harrington,Theonest K. Mutabingwa,François Nosten and Patrick E. Duffy
Reference: 
The Journal of Infectious Diseases 2010;202:000–000

Using frozen‐section histologic evaluation in Tanzania (high‐transmission area), we established a novel grading scheme to separately quantify inflammation and pigment deposition during placental malaria (n=102 ).

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