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monoclonal antibodies

Open Access : Suppressive and additive effects in protection mediated by combinations of monoclonal antibodies specific for merozoite surface protein 1 of Plasmodium yoelii

February 16, 2010 - 13:33 -- Ingeborg van Schayk
Author(s): 
Irosoki Eslava, Gilberto Payares, Beatriz M Pernia, Anthony A Holder, Lilian M Spencer
Reference: 
Malaria Journal 2010, 9:46 (10 February 2010)

These results suggest that a combination of protective antibodies with either the same or different isotypes can produce either an additive or a suppressive effect in passive immunization. This phenomenon may be important in better understanding immunity in this experimental mouse model of malaria.

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