The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10241 malaria professionals are enjoying the free benefits of MalariaWorld today

immunity

Open Access | The interaction of seasonal forcing and immunity and the resonance dynamics of malaria

January 10, 2010 - 15:04 -- Ingeborg van Schayk
Author(s): 
Dylan Z. Childs and Michael Boots
Reference: 

J R Soc Interface. 2010; 7:309-319.

We discuss the implications of our results for understanding prevalence patterns in long-term malaria datasets from Kenya that show multi-annual cycles and one from Thailand that does not and discuss the possible implications of treatment.

Technology: 
Country: 
Medical Condition: 

Plasmepsin 4-Deficient Plasmodium berghei Are Virulence Attenuated and Induce Protective Immunity against Experimental Malaria

December 30, 2009 - 08:13 -- Patrick Sampao
Author(s): 
Roberta Spaccapelo, Chris J. Janse, Sara Caterbi, Blandine Franke-Fayard{dagger, J. Alfredo Bonilla, Luke M. Syphard, Manlio Di Cristina, Tania Dottorini, Andrea Savarino, Antonio Cassone, Francesco Bistoni, Andrew P. Waters, John B. Dame and Andrea Crisanti
Reference: 
American Journal of Pathology. 2010; 176:205-217

Parasite blood-stage attenuation should help identify protective immune responses against malaria, unravel parasite-derived factors involved in malarial pathologies, such as cerebral malaria, and potentially pave the way for blood-stage whole organism vaccines.

The relationship of Plasmodium falciparum humeral immunity with HIV-1 immunosuppression and treatment efficacy in Zambia

November 26, 2009 - 11:57 -- Ingeborg van Schayk
Tags: 
Author(s): 
Jean-Pierre Van geertruyden, Erika Van Eijk, Francisca Yosaatmadja, Webster Kasongo, Modest Mulenga, Umberto D'Alessandro, Stephen Rogerson
Reference: 
Malaria Journal 2009, 8:258 (18 November 2009)

This study reports the impact of HIV-1 infection and other variables on the level of malaria humoral immunity in adults with clinical malaria and whether humoral immune suppression was a risk factor for treatment failure.

Country: 

Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells

November 10, 2009 - 12:58 -- Ingeborg van Schayk
Author(s): 
Nadine Fievet, Stefania Varani, Samad Ibitokou, Valerie Briand, Stephanie Louis, Rene-Xavier Perrin, Achille Massougbodji, Anne Hosmalin, Marita Troye-Blomberg, Philippe Deloron
Reference: 
Malaria Journal 2009, 8:251 (5 November 2009)

The findings support the view that placental parasitization is significantly associated with partial maturation of different dendritic cell subsets and also to slightly increased responses to TLR9 ligand in cord blood.

What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity

October 29, 2009 - 12:37 -- Ingeborg van Schayk
Author(s): 
Samson M Kinyanjui, Philip Bejon, Faith H Osier, Peter C Bull, Kevin Marsh
Reference: 
Malaria Journal 2009, 8:242 (28 October 2009)

Failure to distinguish between individuals who do not get a clinical episode during follow-up because they were unexposed and those who are genuinely immune undermines our ability to assign a protective role to immune responses against malaria. The brevity of antibodies responses makes it difficult to assign the true serological status of an individual at any given time, i.e. those positive at a survey may be negative by the time they encounter the next infection.

Medical Condition: 

Pages

Subscribe to RSS - immunity