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Duffy Binding Protein

Naturally Acquired Antibodies to Plasmodium vivax Duffy Binding Protein (DBP) in Rural Brazilian Amazon

February 10, 2010 - 13:38 -- Ingeborg van Schayk
Author(s): 
Flávia A. Souza-Silva, Mônica da Silva-Nunes, Bruno A. M. Sanchez, Isabela P. Ceravolo, Rosely S. Malafronte, Cristiana F. A. Brito, Marcelo U. Ferreira, AND Luzia H. Carvalho
Reference: 
Am J Trop Med Hyg 2010;82 185-193

Duffy binding protein (DBP), a leading malaria vaccine candidate, plays a critical role in Plasmodium vivax erythrocyte invasion. Sixty-eight of 366 (18.6%) subjects had IgG anti-DBP antibodies by enzyme-linked immunosorbent assay (ELISA) in a community-based cross-sectional survey in the Brazilian Amazon Basin.

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