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falciparum malaria

Open Access | Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies

April 8, 2010 - 07:36 -- Kabogo Ndegwa
C Joos, L Marrama, HE Polson, S Corre, AM Diatta, B Diouf, JF Trape, A Tall, S Longacre, R Perraut
PLoS One (2010) 5: e9871

Effective vaccines to combat malaria are urgently needed, but have proved elusive in the absence of validated correlates of natural immunity.

Open Access | Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children

February 17, 2010 - 20:32 -- Ingeborg van Schayk
Akintunde Sowunmi, Elsie O Adewoye, Grace O Gbotsho, Christian T Happi, Abayomi Sijuade, Onikepe A Folarin, Titilope M Okuboyejo, Obaro S Michael
Malaria Journal 2010, 9:53 (15 February 2010)

The study reports on the relationship between delay in parasite clearance and anti-malarial treatment failure in children with falciparum malaria in an area of intense transmission in south-western Nigeria.


Review: Do paediatric drug formulations of artemisinin combination therapies improve the treatment of children with A systematic review and meta-analysis

January 28, 2010 - 12:47 -- Kabogo Ndegwa
Florian Kurth, Sabine Bélard, Ayola A Adegnika, Prof Oumar Gaye, Prof Peter G Kremsner, and Dr Michael Ramharter
The Lancet Infectious Diseases, Volume 10, Issue 2, February 2010, Pages 125-132

These data provide, for the first time, evidence for improved management of children by use of paediatric formulations, and support the further development and use of paediatric ACTs.

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