This study highlights the need for conducting further studies to investigate the association of antibodies against SE36 and outcomes of malaria infection in pregnant women.
The findings of this study demonstrated comparable capacity for detecting severe falciparum malaria using circulatory collapse, severe anemia or parasitemia.
Plasmodium falciparum malaria claims 1 million lives around the globe every year.
This review describes recent developments to decrease the cost and run time, and increase the ease of use of NAT while maintaining their high sensitivity and specificity and low limit of detection at the point-of-care.
To detect pre-patent parasitemia, we developed a real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) for the asexual 18S ribosomal RNA (rRNAs) of Plasmodium falciparum.
In this study, we used a benchtop nuclear magnetic resonance (NMR) device to detect hemozoin. This device could be deployed in malaria-endemic settings.
Malaria infection leads to anemia in humans which generally occurs during the chronic phase of the infection.
It is considered that several glycoproteins on erythrocytes in mammalian species are involved in malaria parasite infection.
These results suggest that the quantitative and qualitative changes in the dendritic cell compartment are important for the pathogenesis of ECM.
The rapid, accurate diagnosis of Plasmodium spp. is essential for the effective control of malaria, especially in asymptomatic infections.