Severe falciparum malaria is associated with hypoargininemia, which contributes to impaired systemic and pulmonary NO production and endothelial dysfunction.
Discussed are the medical and technical considerations on the use of adjunctive ET for severe P. falciparum infection and a review of the literature of the use of adjunct ET in the treatment of severe P. falciparum malaria.
We propose a numerical model of hemodynamics arising from malaria infection. This model is based on a particle method, where all the components of blood are represented by the finite number of particles.
A recent study published in Nature by de Koning-Ward et al. provides further insights into the way in which the lethal malaria parasite, Plasmodium falciparum, remodels the host red blood cell during the pathogenic blood stage of development.
