The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10623 malaria professionals are enjoying the free benefits of MalariaWorld today

malaria parasite

Open Access | Inferred relatedness and heritability in malaria parasites

April 19, 2010 - 13:24 -- Kabogo Ndegwa
Author(s): 
TJ Anderson, JT Williams, S Nair, D Sudimack, M Barends, A Jaidee, RN Price, F Nosten
Reference: 
Proc Biol Sci, April 14, 2010

Malaria parasites vary in phenotypic traits of biomedical or biological interest such as growth rate, virulence, sex ratio and drug resistance, and there is considerable interest in identifying the genes that underlie this variation.

Medical Condition: 

Open Access | An acid-loading chloride transport pathway in the intraerythrocytic malaria parasite, Plasmodium falciparum

April 9, 2010 - 06:58 -- Patrick Sampao
Author(s): 
Roselani I. Henry, Simon A. C., Richard J., et al
Reference: 
The Journal of Biological Chemistry

In this study, a combination of fluorescent ion indicators and 36Cl- flux measurements was used to investigate the transport of Cl- and the Cl- dependent transport of "H+ equivalents" in mature (trophozoite-stage) parasites, isolated from their host erythrocytes.

Technology: 

Structure and Function of a G-actin Sequestering Protein with a Vital Role in Malaria Oocyst Development inside the Mosquito Vector

April 9, 2010 - 06:37 -- Patrick Sampao
Author(s): 
Marion Hliscs, Julia M. Sattler, Wolfram Tempe, Jennifer D. Artz, Aiping Dong, Raymond Hui, Kai Matuschewski, Herwig Schüle
Reference: 
The Journal of Biological Chemistry

Our results reveal a specific vital role for an apicomplexan G-actin-binding protein during sporogony, the parasite replication phase that precedes formation of malaria transmission stages. 

Cellular Immunology and Immune Regulation: Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses

April 8, 2010 - 13:14 -- Kabogo Ndegwa
Author(s): 
Xianzhu Wu, Nagaraj M. Gowda, Sanjeev Kumar, and D. Channe Gowda
Reference: 
The Journal of Immunology, 2010, Volume 184, Issue 8 Pages 4338 -4348

Dendritic cells (DCs) play a crucial role in the development of protective immunity to malaria. However, it remains unclear how malaria parasites trigger immune responses in DCs.

Open Access | Long-Lived Antibody and B Cell Memory Responses to the Human Malaria Parasites, Plasmodium falciparum and Plasmodium vivax

February 27, 2010 - 09:29 -- Ingeborg van Schayk
Author(s): 
Jiraprapa Wipasa, Chaisuree Suphavilai, Lucy C. Okell, Jackie Cook, Patrick H. Corran, Kanitta Thaikla, Witaya Liewsaree, Eleanor M. Riley, Julius Clemence R. Hafalla
Reference: 
PLoS Pathog 6(2): e1000770

In this study, we analysed the longevity of both antibody and B cell memory responses to malaria antigens among individuals who were living in an area of extremely low malaria transmission in northern Thailand, and who were known either to be malaria naïve or to have had a documented clinical attack of P. falciparum and/or P. vivax in the past 6 years.

Country: 

Open Access | Distinct External Signals Trigger Sequential Release of Apical Organelles during Erythrocyte Invasion by Malaria Parasites

February 11, 2010 - 13:53 -- Ingeborg van Schayk
Author(s): 
Shailja Singh, M. Mahmood Alam, Ipsita Pal-Bhowmick, Joseph A. Brzostowski, Chetan E. Chitnis
Reference: 
PLoS Pathog 6(2): e1000746

 

The invasion of erythrocytes by Plasmodium merozoites requires specific interactions between host receptors and parasite ligands. We have used time-lapse video microscopy to study changes in intracellular calcium levels in Plasmodium falciparum merozoites during erythrocyte invasion.

Open Access | Home Improvements: How the Malaria Parasite Makes the Red Blood Cell Home Sweet Home

January 23, 2010 - 17:37 -- Ingeborg van Schayk
Author(s): 
G. Lucas Starnes and Andrew P. Waters
Reference: 
J Mol Cell Biol. 2010; 2:11-13

A recent study published in Nature by de Koning-Ward et al. provides further insights into the way in which the lethal malaria parasite, Plasmodium falciparum, remodels the host red blood cell during the pathogenic blood stage of development.

Medical Condition: 

Pages

Subscribe to RSS - malaria parasite