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anopheles gambiae

Open Access | PNAS Plus: Requirements for effective malaria control with homing endonuclease genes

October 26, 2011 - 14:11 -- Kabogo Ndegwa
Author(s): 
Anne Deredec, H. Charles J. Godfray, and Austin Burt
Reference: 
PNAS October 25, 2011 vol. 108 no. 43 E874-E880

MalariaWorldMalaria continues to impose a substantial burden on human health. We have previously proposed that biological approaches to control the mosquito vector of disease could be developed using homing endonuclease genes (HEGs), a class of selfish or parasitic gene that exists naturally in many microbes.

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Matrix-assisted laser desorption/ionization-mass spectrometry of cuticular lipid profiles can differentiate sex, age, and mating status of Anopheles gambiae mosquitoes

October 26, 2011 - 07:00 -- Kabogo Ndegwa
Author(s): 
Estrella Suarez, Hien P. Nguyen, Israel P. Ortiz, Kyu Jong Lee, Seoung Bum Kim, Jaroslaw Krzywinski, Kevin A. Schug
Reference: 
Analytica Chimica Acta, Volume 706, Issue 1, 7 November 2011, Pages 157-163

MalariaWorldMalaria is a devastating mosquito-borne disease, which affects hundreds of millions of people each year.

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Infection Intensity-Dependent Responses of Anopheles gambiae to the African Malaria Parasite Plasmodium falciparum

October 17, 2011 - 08:29 -- Patrick Sampao
Author(s): 
Antonio M. Mendes, Parfait H. Awono-Ambene, Sandrine E. Nsango, Anna Cohuet, Didier Fontenille, Fotis C. Kafatos, George K. Christophides, Isabelle Morlais, and Dina Vlachou
Reference: 
Infect. Immun., Nov 2011; 79: 4708 - 4715.

MalariaWorldThese data suggest that coadaptation between vectors and parasites may act to minimize the impact of infection on mosquito fitness by selectively suppressing specific functional classes of genes.

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Open Access | Sensitivity of Anopheles gambiae population dynamics to meteo-hydrological variability: a mechanistic approach

October 11, 2011 - 07:26 -- Kabogo Ndegwa
Author(s): 
Gilioli G, Mariani L
Reference: 
Malaria Journal 2011, 10:294 (10 October 2011)

MalariaWorldThe non-linear temperature-dependent response is in agreement with the non-linear patterns of temperature-response of the basic bio-demographic processes.

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Open Access | Population genetic structure of Anopheles arabiensis and Anopheles gambiae in a malaria endemic region of southern Tanzania

October 10, 2011 - 09:06 -- Kabogo Ndegwa
Author(s): 
Ng'habi KR, Knols BG, Lee Y, Ferguson HM, Lanzaro GC
Reference: 
Malaria Journal 2011, 10:289 (5 October 2011)

MalariaWorldIt was hypothesized that ecological diversification across the valley may be a driving force for observed An. arabiensis genetic divergence.

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Dramatic Decrease in Malaria Transmission after Large-Scale Indoor Residual Spraying with Bendiocarb in Benin, an Area of High Resistance of Anopheles gambiae to Pyrethroids

October 10, 2011 - 08:24 -- Patrick Sampao
Author(s): 
Martin Akogbeto, Gil Germain Padonou, Honore Sourou Bankole, Dorothee Kinde Gazard and Ghelus Louis Gbedjissi
Reference: 
Am J Trop Med Hyg 2011 85:586-593

MalariaWorldThe study has shown a drastic decrease in the An. gambiae biting rate in the sprayed areas. Results of an enzyme-linked immunosorbent assay were negative for Plasmodium falciparum antigen during the entire period of the intervention.

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Open Access | Comparative susceptibility to Plasmodium falciparum of the molecular forms M and S of Anopheles gambiae and Anopheles arabiensis

September 21, 2011 - 13:56 -- Patrick Sampao
Author(s): 
Mamadou O Ndiath, Anna Cohuet, Ablaye Gaye, Lassana Konate, Catherine Mazenot, Ousmane Faye, Christian Boudin, Cheikh Sokhna and Jean-Francois Trape
Reference: 
Malaria Journal 2011, 10:269

The aim of this study was to compare the susceptibility of M and S molecular forms of Anopheles gambiae and Anopheles arabiensis to infection by Plasmodium falciparum.

Optimization of the Gal4-UAS system in an Anopheles gambiae cell line

September 20, 2011 - 13:22 -- Patrick Sampao
Author(s): 
A. Lynd, G. J. Lycett
Reference: 
Insect Molecular Biology, Volume 20, Issue 5, pages 599–608, October 2011

The results indicated that the native Gal4 is only weakly active in these cells. Modified forms of Gal4, including those carrying minimal VP16 activation domains, as well as a deleted form of Gal4, give up to 20-fold greater activity than the native protein, when used in conjunction with a responder plasmid having 14 UAS repeats.

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Open Access | The Interplay between Tubulins and P450 Cytochromes during Plasmodium berghei Invasion of Anopheles gambiae Midgut

September 7, 2011 - 06:37 -- Kabogo Ndegwa
Author(s): 
Rute C. Félix, Henrique Silveira
Reference: 
PLoS ONE 6(8): e24181

Our results suggest the existence of a relationship between tubulins and P450 cytochromes during A. gambiae immune response to P. berghei invasion.

Open Access | Spermless males elicit large-scale female responses to mating in the malaria mosquito Anopheles gambiae

August 17, 2011 - 07:37 -- Kabogo Ndegwa
Author(s): 
Janis Thailayil, Kalle Magnusson, H. Charles J. Godfray, Andrea Crisanti, and Flaminia Catteruccia
Reference: 
PNAS August 16, 2011 vol. 108 no. 33 13677-13681

Anopheles gambiae sensu stricto is the major vector of malaria, a disease with devastating consequences for human health.

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