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anopheles gambiae

Susceptibility of Anopheles gambiae s.l. to DDT, malathion, permethrin and deltamethrin in Ethiopia

March 17, 2011 - 08:56 -- Kabogo Ndegwa
Author(s): 
Alemayehu Abate and Mamuye Hadis
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 4, pages 486–491, April 2011

The existence of high level of DDT and pyrethroid resistance with the possibility of cross-resistance to each other and other classes of agricultural pesticides could seriously jeopardise the efficacy of both ITNs and IRS in the country in the future.

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Open Access | Exceptional Diversity, Maintenance of Polymorphism, and Recent Directional Selection on the APL1 Malaria Resistance Genes of Anopheles gambiae

March 11, 2011 - 08:32 -- Kabogo Ndegwa
Author(s): 
Susan M. Rottschaefer, Michelle M. Riehle, Boubacar Coulibaly, Madjou Sacko, Oumou Niaré, Isabelle Morlais, Sekou F. Traoré, Kenneth D. Vernick, Brian P. Lazzaro
Reference: 
PLoS Biol 9(3): e1000600

The three-gene APL1 locus encodes essential components of the mosquito immune defense against malaria parasites.

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Coadaptation of isoacceptor tRNA genes and codon usage bias for translation efficiency in Aedes aegypti and Anopheles gambiae

March 7, 2011 - 08:24 -- Patrick Sampao
Author(s): 
S. K. Behura, D. W. Severson
Reference: 
Insect Molecular Biology, Volume 20, Issue 2, pages 177–187, April 2011

Our results suggest that these genes and the related pathways may be under translational selection in these mosquitoes.

Open Access | Larvicidal activity of metabolites from the endophytic Podospora sp. against the malaria vector Anopheles gambiae

February 24, 2011 - 07:45 -- Kabogo Ndegwa
Author(s): 
Josphat C. Matasyoh, Birger Dittrich, Anja Schueffler & Hartmut Laatsch
Reference: 
Parasitology Research, Volume 108, Number 3, 561-566, DOI: 10.1007/s00436-010-2098-1

In a screening for natural products with mosquito larvicidal activities, the endophytic fungus Podospora sp. isolated from the plant Laggera alata (Asteraceae) was conspicuous.

Open Access | Wolbachia Infections in Anopheles gambiae Cells: Transcriptomic Characterization of a Novel Host-Symbiont Interaction

February 23, 2011 - 09:43 -- Kabogo Ndegwa
Author(s): 
Grant L. Hughes, Xiaoxia Ren, Jose L. Ramirez, Joyce M. Sakamoto, Jason A. Bailey, Anne E. Jedlicka, Jason L. Rasgon
Reference: 
PLoS Pathog 7(2): e1001296

The endosymbiotic bacterium Wolbachia is being investigated as a potential control agent in several important vector insect species.

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Open Access| The “Far-West” of Anopheles gambiae Molecular Forms

February 17, 2011 - 06:33 -- Kabogo Ndegwa
Author(s): 
Beniamino Caputo, Federica Santolamazza, José L. Vicente, Davis C. Nwakanma, Musa Jawara, Katinka Palsson, Thomas Jaenson, Bradley J. White, Emiliano Mancini, Vincenzo Petrarca, David J. Conway, Nora J. Besansky, João Pinto, Alessandra della Torre
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PLoS ONE 6(2): e16415

The main Afrotropical malaria vector, Anopheles gambiae sensu stricto, is undergoing a process of sympatric ecological diversification leading to at least two incipient species (the M and S molecular forms) showing heterogeneous levels of divergence across the genome.

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Open Access | Improvement of a synthetic lure for Anopheles gambiae using compounds produced by human skin microbiota

February 10, 2011 - 06:53 -- Kabogo Ndegwa
Author(s): 
Verhulst NO, Mbadi PA, Bukovinszkine Kiss G, Mukabana WR, van Loon JJ, Takken W, Smallegange RC
Reference: 
Malaria Journal 2011, 10:28 (8 February 2011)

Identification of volatiles released by human skin bacteria led to the discovery of compounds that have an impact on the host-seeking behaviour of A. gambiae.

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Open Access | Identification of a fibrinogen-related protein (FBN9) gene in neotropical anopheline mosquitoes

February 9, 2011 - 07:04 -- Kabogo Ndegwa
Author(s): 
Oliveira SB, Ibraim IC, Tadei WP, Ruiz JC, Nahum LA, Brito CF, Moreira LA
Reference: 
Malaria Journal 2011, 10:21 (2 February 2011)

The present work adds new insights into the conserved role of fbn9 in insect immunity in a broader range of anopheline species and reinforces the possibility of manipulating mosquito immunity to design novel pathogen control strategies.

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Open Access | Evolutionary Dynamics of the Ty3/Gypsy LTR Retrotransposons in the Genome of Anopheles gambiae

February 2, 2011 - 06:41 -- Kabogo Ndegwa
Author(s): 
Jose Manuel C. Tubio, Marta Tojo, Laia Bassaganyas, Georgia Escaramis, Igor V. Sharakhov, Maria V. Sharakhova, Cristian Tornador, Maria F. Unger, Horacio Naveira, Javier Costas, Nora J. Besansky
Reference: 
PLoS ONE 6(1): e16328

Ty3/gypsy elements represent one of the most abundant and diverse LTR-retrotransposon (LTRr) groups in the Anopheles gambiae genome, but their evolutionary dynamics have not been explored in detail.

Open Access | Site-Specific Integration and Expression of an Anti-Malarial Gene in Transgenic Anopheles gambiae Significantly Reduces Plasmodium Infections

February 2, 2011 - 06:33 -- Kabogo Ndegwa
Author(s): 
Janet M. Meredith, Sanjay Basu, Derric D. Nimmo, Isabelle Larget-Thiery, Emma L. Warr, Ann Underhill, Clare C. McArthur, Victoria Carter, Hilary Hurd, Catherine Bourgouin, Paul Eggleston
Reference: 
PLoS ONE 6(1): e14587

Diseases transmitted by mosquitoes have a devastating impact on global health and this is worsening due to difficulties with existing control measures and climate change.

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