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stem cell growth factor

A Novel Functional Variant in the Stem Cell Growth Factor Promoter Protects against Severe Malarial Anemia

January 10, 2010 - 14:27 -- Ingeborg van Schayk
Author(s): 
Collins Ouma, Christopher C. Keller, Gregory C. Davenport, Tom Were, Stephen Konah, Michael F. Otieno, James B. Hittner, John M. Vulule, Jeremy Martinson, John M. Ong'echa, Robert E. Ferrell, and Douglas J. Perkins
Reference: 
Infect. Immun. 2010;78 453-460

The results presented here demonstrate that homozygous T at –539 in the SCGF promoter is associated with elevated SCGF production, enhanced erythropoiesis, and protection against the development of SMA in children with falciparum malaria.

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