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Anopheles stephensi

Open Access | Plasmodium falciparum Malaria Challenge by the Bite of Aseptic Anopheles stephensi Mosquitoes: Results of a Randomized Infectivity Trial

October 30, 2010 - 12:24 -- Kabogo Ndegwa
Author(s): 
Kirsten E. Lyke, Matthew Laurens, Matthew Adams, Peter F. Billingsley, Adam Richman, Mark Loyevsky, Sumana Chakravarty, Christopher V. Plowe, B. Kim Lee Sim, Robert Edelman, Stephen L. Hoffman
Reference: 
PLoS ONE 5(10): e13490

The use of aseptic, cGMP-compliant P. falciparum-infected mosquitoes is safe, is associated with a precise prepatent period compared to the standard model and appears more efficient than the standard approach, as it led to infection in 100% (6/6) of volunteers exposed to three mosquito bites and 83% (5/6) of volunteers exposed to one mosquito bite.

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Short Communication: Chemical composition and larvicidal activity of the essential oil of Plectranthus amboinicus (Lour.) Spreng against Anopheles stephensi: a malarial vector mosquito

October 8, 2010 - 07:10 -- Kabogo Ndegwa
Author(s): 
Annadurai Senthilkumar & Venugopalan Venkatesalu
Reference: 
Parasitology Research, Volume 107, Number 5, 1275-1278, Essential oil of Plectranthus

Essential oil of Plectranthus amboinicus was studied for its chemical composition and larvicidal potential against the malarial vector mosquito Anopheles stephensi. Totally 26 compounds were identified by GC and GC-MS.

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Open Access | Activation of Akt Signaling Reduces the Prevalence and Intensity of Malaria Parasite Infection and Lifespan in Anopheles stephensi Mosquitoes

July 19, 2010 - 08:46 -- Kabogo Ndegwa
Author(s): 
Vanessa Corby-Harris, Anna Drexler, Laurel Watkins de Jong, Yevgeniya Antonova, Nazzy Pakpour, Rolf Ziegler, Frank Ramberg, Edwin E. Lewis, Jessica M. Brown, Shirley Luckhart, Michael A. Riehle
Reference: 
PLoS Pathog 6(7): e1001003

Thus, we demonstrate that genetic manipulation of one key signaling protein directly reduces parasite development in the insect vector as well as the duration of mosquito infectivity.

Open Access | Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi: a case study in Mangalore city, South India

June 24, 2010 - 10:29 -- Kabogo Ndegwa
Author(s): 
Tiwari S, Ghosh SK, Ojha VP, Dash AP, Raghavendra K
Reference: 
Malaria Journal 2010, 9:179 (23 June 2010)

Susceptibility of An. stephensi to DDT is an important finding as this has never been used in Mangalore city, whereas its rural counterpart Anopheles culicifacies is widely resistant to this insecticide. The study explores the selection and rotation of the appropriate insecticide molecule even within the same group for effective vector management.

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Molecular characterization of carboxypeptidase B (CPB) of An. stephensi with respect to TBV strategy in states under WHO/EMRO

March 17, 2010 - 09:00 -- Ingeborg van Schayk
Author(s): 
A. Raz, N. Dinparast Djadid, S. Zakeri
Reference: 
New Biotechnology, Volume 27, Supplement 1, April 2010, Page S30

No abstract available 

Short Communication: Comparative fitness assessment of Anopheles stephensi transgenic lines receptive to site-specific integration

March 11, 2010 - 12:34 -- Patrick Sampao
Author(s): 
D. A. Amenya, M. Bonizzoni, A. T. Isaacs, N. Jasinskiene, H. Chen, O. Marinotti, G. Yan, A. A. James
Reference: 
Insect Molecular Biology, Volume 19, Issue 2,April 2010, Pages: 263-269

Genetically modified mosquitoes that are unable to transmit pathogens offer opportunities for controlling vector-borne diseases such as malaria and dengue.

Open Access | Transmission blocking activity of a standardized neem (Azadirachta indica) seed extract on the rodent malaria parasite Plasmodium berghei in its vector Anopheles stephensi

March 7, 2010 - 13:02 -- Ingeborg van Schayk
Author(s): 
Leonardo Lucantoni, Rakiswende S Yerbanga, Giulio Lupidi, Luciano Pasqualini, Fulvio Esposito, Annette Habluetzel
Reference: 
Malaria Journal 2010, 9:66 (2 March 2010)

These results and evidence of anti-plasmodial activity of neem products accumulated over the last years encourage to convey neem compounds into the drug discovery & development pipeline and to evaluate their potential for the design of novel or improved transmission-blocking remedies.

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Open Access | Plasmodium yoelii-Infected A. stephensi Inefficiently Transmit Malaria Compared to Intravenous Route

February 9, 2010 - 13:32 -- Ingeborg van Schayk
Author(s): 
Solomon Conteh, Rana Chattopadhyay, Charles Anderson, Stephen L. Hoffman
Reference: 
PLoS ONE 5(1): e8947

Such data may have implications for determining the best route and dose of administration to humans of our attenuated P. falciparum sporozoite vaccine, the scientific basis of which is immunity by bites from irradiated infected mosquitoes, and suggest that the challenge is to develop a method of administration that approximates IV inoculation, not one that mimics mosquito bite.

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Open Access | Factors affecting fungus-induced larval mortality in Anopheles gambiae and Anopheles stephensi

January 20, 2010 - 09:29 -- Ingeborg van Schayk
Author(s): 
Tullu Bukhari, Anthonieke Middelman, Constantianus JM Koenraadt, Willem Takken, Bart GJ Knols
Reference: 
Malaria Journal 2010, 9:22 (19 January 2010)

Further data on an interesting new approach for biological mosquito larval control.

Open Access | Ecology: Identification and characterization of odorant-binding protein 1 gene from the Asian malaria mosquito, Anopheles stephensi

January 6, 2010 - 12:56 -- Patrick Sampao
Author(s): 
M. S. Sengul, Z. Tu
Reference: 
Insect Molecular Biology : Volume 19, Issue 1, Date: February 2010, Pages: 49-60

Here we report the identification and molecular characterization of the Anopheles stephensi odorant-binding protein 1 gene (AsteObp1), an Obp1 gene in An. stephensi, a major malaria vector in Asia.

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