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Plasmodium infection

Contributions of natural killer cells to the immune response against Plasmodium

September 23, 2019 - 14:49 -- Open Access
Author(s): 
Kristina S. Burrack, Geoffrey T. Hart and Sara E. Hamilton
Reference: 
Malaria Journal 2019 18:321, 18 September 2019

Natural killer (NK) cells are important innate effector cells that are well described in their ability to kill virally-infected cells and tumors.

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Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles

November 11, 2012 - 09:53 -- Open Access
Author(s): 
Binh V. Le, Marni Williams, Shankar Logarajah, Richard H. G. Baxter
Reference: 
PLoS Pathog 8(10): e1002958
MalariaWorld

Thioester-containing protein 1 (TEP1) is a central component in the innate immune response of Anopheles gambiae to Plasmodium infection.

Alterations in Bone and Erythropoiesis in Hemolytic Anemia: Comparative Study in Bled, Phenylhydrazine-Treated and Plasmodium-Infected Mice

October 8, 2012 - 09:11 -- Kabogo Ndegwa
Author(s): 
Robert Moreau, Diane Tshikudi Malu, Mathieu Dumais, Esther Dalko, Véronique Gaudreault, Hugo Roméro, Corine Martineau, Olha Kevorkova, Jaime Sanchez Dardon, Erin Lynn Dodd, David Scott Bohle, Tatiana Scorza
Reference: 
PLoS ONE 7(9): e46101

MalariaWorldSustained erythropoiesis and concurrent bone marrow hyperplasia are proposed to be responsible for low bone mass density (BMD) in chronic hemolytic pathologies.

Control of immunopathology during Plasmodium infection by hepcidin

December 28, 2011 - 13:05 -- Patrick Sampao
Author(s): 
Ivo Marguti
Reference: 
Medical Hypotheses, Volume 78, Issue 2, February 2012, Pages 250-253

MalariaWorldHerein the hypothesis that hemoglobinopathies afford protection against severe forms of malaria by limiting exacerbated immune activation, via a mechanism that involves low hepcidin expression, is discussed.

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Review: A toolbox to study liver stage malaria

November 21, 2011 - 12:41 -- Patrick Sampao
Author(s): 
Miguel Prudêncio, Maria M. Mota, António M. Mendes
Reference: 
Trends in Parasitology, Volume 27, Issue 12, December 2011, Pages 565-574

MalariaWorldHere, we review appropriate infection models and infection assessment tools, and provide a comprehensive description of recent advances in experimental strategies to investigate the liver stage of malaria.

Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection

August 30, 2011 - 12:06 -- Patrick Sampao
Author(s): 
Ashraful Haque, Shannon E. Best, Christian R. Engwerda, et al.
Reference: 
European Journal of Immunology, Volume 41, Issue 9, pages 2688–2698, September 2011

Here, we observed IFN-α protein production in the spleen of PbA-infected C57BL/6 mice over the first 2 days of infection.

Open Access | Prevalence of anopheline species and their Plasmodium infection status in epidemic-prone border areas of Bangladesh

January 14, 2010 - 12:20 -- Ingeborg van Schayk
Author(s): 
Mohammad Shafiul Alam, Md. Gulam Musawwir Khan, Nurunnabi Chaudhury, Sharmina Deloer, Forida Nazib, A Mannan Bangali, Rashidul Haque
Reference: 
Malaria Journal 2010, 9:15 (14 January 2010)

The manuscript contains valuable data on Anopheline species prevalence and their infection status in malaria epidemic-prone area in Bangladesh.

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Open Access | Plasmodium infection and its risk factors in eastern Uganda

January 7, 2010 - 13:40 -- Ingeborg van Schayk
Author(s): 
Rachel L Pullan, Hasifa Bikirwa, Sarah G Staedke, Robert W Snow, Simon Brooker
Reference: 
Malaria Journal 2010, 9:2 (4 January 2010)

These findings demonstrate that mosquito net usage remains inadequate and is strongly associated with risk of malaria among school-aged children. Infection risk amongst adults is influenced by proximity to potential mosquito breeding grounds.

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