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Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria

December 29, 2009 - 12:39 -- Patrick Sampao
Anne-Marit Sponaas, Ana Paula Freitas do Rosario, Cecile Voisine, Beatris Mastelic, Joanne Thompson, Sandra Koernig, William Jarra, Laurent Renia, Marjorie Mauduit, Alexandre J. Potocnik, and Jean Langhorne
Blood, 24 December 2009, Vol. 114, No. 27, pp. 5522-5531.

During Plasmodium chabaudi infection in mice, a population of CD11bhighLy6C+ monocytes are generated in bone marrow, most of which depend on the chemokine receptor CCR2 for migration from bone marrow to the spleen.

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