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monocytes

Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria

December 29, 2009 - 12:39 -- Patrick Sampao
Author(s): 
Anne-Marit Sponaas, Ana Paula Freitas do Rosario, Cecile Voisine, Beatris Mastelic, Joanne Thompson, Sandra Koernig, William Jarra, Laurent Renia, Marjorie Mauduit, Alexandre J. Potocnik, and Jean Langhorne
Reference: 
Blood, 24 December 2009, Vol. 114, No. 27, pp. 5522-5531.

During Plasmodium chabaudi infection in mice, a population of CD11bhighLy6C+ monocytes are generated in bone marrow, most of which depend on the chemokine receptor CCR2 for migration from bone marrow to the spleen.

Medical Condition: 
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