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host immunity

Review: Host immunity as a determinant of treatment outcome in Plasmodium falciparum malaria

December 29, 2009 - 13:52 -- Patrick Sampao
Prof Stephen J Rogerson FRACP, Rushika S Wijesinghe MD, and Steven R Meshnick MD
The Lancet Infectious Diseases, Volume 10, Issue 1, January 2010, Pages 51-59

Improved methods for assessing antimalarial immunity will strengthen malaria control efforts.

Medical Treatment: 

Open Access | Plasmodium falciparum var gene expression is modified by host immunity

December 24, 2009 - 14:25 -- Ingeborg van Schayk
George M. Warimwe, Thomas M. Keane, Gregory Fegan, Jennifer N. Musyoki, Charles R. J. C. Newton, Arnab Pain, Matthew Berriman, Kevin Marsh, and Peter C. Bull
PNAS December 22, 2009 vol. 106 no. 51 21801-21806

Here, in a study of 217 Kenyan children with malaria, we show that expression of a group of var genes “cys2,” containing a distinct pattern of cysteine residues, is associated with low host immunity.

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