Open Access | Chloroquine reduces arylsulphatase B activity and increases chondroitin 4-sulphate: implications for mechanisms of action and resistance
Reference:
Malaria Journal 2009, 8:303 (17 December 2009)
If chloroquine reduced ASB activity, leading to increased chondroitin-4-sulphation, it was hypothesized that the anti-malarial mechanism of chloroquine might derive, at least in part, from suppression of ASB.
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