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Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study

September 6, 2012 - 06:40 -- Kabogo Ndegwa
Author(s): 
Anna Rosanas-Urgell, Enmoore Lin, Ivo Mueller, et al.
Reference: 
PLoS Med 9(9): e1001305

MalariaWorldIn three independent studies, we observed strong associations between SAO and protection against P. vivax malaria by a mechanism that is independent of the Duffy antigen. P. vivax malaria may have contributed to shaping the unique host genetic adaptations to malaria in Asian and Oceanic populations.

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