Here, we test the hypothesis that virulent malaria parasites are less susceptible to drug treatment than less virulent parasites.
Increasing evidence critically implicates miRNAs in the pathogenesis of diseases, but little is known in context with infectious diseases.
Malaria vaccine developers are concerned that antigenic escape will erode vaccine efficacy.
Derivatives of 7-benzylidenenaltrexone (BNTX), which was recently reported to be an effective chloroquine (CQ)-resistance reverser, were synthesized and evaluated for their CQ-resistance reversing activities.
Galectins are evolutionarily conserved glycan-binding proteins with pleiotropic roles in innate and adaptive immune responses.
The developed techniques were useful to quantify Hz in different organs with a high reproducibility and sensitivity.
Apical membrane Ag 1 (AMA1) is one of the leading candidate Ags for inclusion in a subunit vaccine against blood-stage malaria.
Loop-mediated isothermal amplification (LAMP) has been increasingly used for diagnosis and quantification of pathogens.
In this model, pir genes are called cirs and may be involved in this mechanism, allowing evasion of host immune responses. In order to fully understand the role(s) of CIR proteins during P. chabaudi infection, a detailed characterization of the cir gene family was required.
The molecular mechanisms that underlie poor birth outcomes in malaria during pregnancy remain poorly defined.