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gomphostenin

Not Open Access | In vitro and in vivo antimalarial evaluation of semi-synthetic derivatives of gomphostenin

June 29, 2012 - 14:09 -- Patrick Sampao
Author(s): 
Manisha Sathe, M.P. Kaushik
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 20, Issue 14, 15 July 2010, Pages 4233-4236

MalariaWorldGN derivatives 3 and 5 were found to have curative activity with moderate chemosuppression of 65% and 69%, respectively, at the dose level of 150 mg/kg/day.

Medical Condition: 
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