The human infectious reservoir for malaria consists of individuals capable of infecting mosquitoes. Oocyst prevalence and density are typical indicators of human infectivity to mosquitoes. However, identification of oocysts is challenging, particularly in areas of low malaria transmission intensity where few individuals may infect mosquitoes, and infected mosquitoes tend to have few oocysts. Here, features that differentiate oocysts from other oocyst-like in mosquito midguts are explained and illustrated. In addition, the establishment and maintenance of infrastructure to perform malaria transmission experiments is described. This work may support other initiatives to set up membrane feeding infrastructure and guide oocyst detection in low transmission settings.
Malaria Journal 2019 18:287, 27 August 2019
Blood Volume: 132 Issue: 8 Pages: 868
A 27-year-old man developed high fever after returning from sub-Saharan Africa.
Acta Tropica, Volume 121, Issue 1, January 2012, Pages 6-12
Describing genetic diversity of the Plasmodium falciparum parasite provides important information about the local epidemiology of malaria.