Open Access | Methodology: Rapid identification of chloroquine and atovaquone drug resistance in Plasmodium falciparum using high-resolution melt polymerase chain reaction
Reference:
Malaria Journal 2010, 9:134 (21 May 2010)
PCR-HRM is an inexpensive option for the determination of drug resistance profile in P. falciparum and will see increasing use as an alternative to sequencing and 5'nuclease PCR assays in reference laboratories or once PCR systems that are able to conduct HRM become commonplace.
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Dr. Dondorp is the Deputy Director and Head of malaria research at the Mahidol-Oxford Research Unit in Bangkok, Thailand, where he plans, coordinates and supervises clinical and laboratory malaria studies.
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