Kinesin-8 proteins are microtubule motors that are often involved in regulation of mitotic spindle length and chromosome alignment.
Malaria is one of the deadliest infectious diseases caused by protozoan parasite of Plasmodium spp. Increasing resistance to anti-malarials has become global threat in control of the disease and demands for novel anti-malarial interventions. Naturally-occurring coumarins, which belong to a class of benzo-α-pyrones, found in higher plants and some essential oils, exhibit therapeutic potential against various diseases. However, their limited uptake and non-specificity has restricted their wide spread use as potential drug candidates.
White-tailed deer (Odocoileus virginianus), an ecologically and economically important species, are the most widely distributed large animals in North America.
We investigated orthologous genes encoding two merozoite proteins, MSP8 and MSP10, among several mammalian Plasmodium spp. These antigens, together with MSP1, are among the few MSPs that have two epidermal growth factor-like domains (EGF) at the C-terminal.
These results, which rely solely on PCR-based examination of feces, validate numerous estimates of the prevalence of malaria in great apes.
Regulation of mRNA translation plays a key part in controlling the life cycle of Plasmodium spp. parasites, the causative agents of malaria.
We describe avian malaria lineages and their seasonal prevalence in 2007-2008 in Saddlebacks from Mokoia Island, a source of birds for translocations, and investigate their pathogenicity.
In early 2010, we administered a questionnaire pertaining to physical fitness to 200 schoolchildren in Cote d'Ivoire. Helminth and Plasmodium spp. infections were determined and schoolchildren's physical fitness objectively measured in a maximal multistage 20 m shuttle run test.