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Nuclear Magnetic Resonance: A Tool for Malaria Diagnosis?

November 3, 2011 - 09:42 -- Patrick Sampao
Stephan Karl, Lucía Gutiérrez, Michael J. House, Timothy M. E. Davis and Tim G. St. Pierre
Am J Trop Med Hyg 2011 85:815-817

MalariaWorldIn this study, we used a benchtop nuclear magnetic resonance (NMR) device to detect hemozoin. This device could be deployed in malaria-endemic settings.

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Open Access | Detection of malarial byproduct hemozoin utilizing its unique scattering properties

June 14, 2011 - 14:48 -- Patrick Sampao
Benjamin K. Wilson, Matthew R. Behrend, Matthew P. Horning, and Michael C. Hegg
Optics Express, Vol. 19, Issue 13, pp. 12190-12196 (2011)

A new detection method is proposed and demonstrated using dark-field in conjunction with cross-polarization imaging and spectroscopy. SNRs greater than 50:1 are achieved for hemozoin in fresh blood without the addition of stains or reagents. The potential of such a detection system is discussed.

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