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Open Access | Review: Severe Malarial Anemia: Innate Immunity and Pathogenesis

November 21, 2011 - 14:56 -- Patrick Sampao
Douglas J. Perkins, Tom Were, Gregory C. Davenport, Prakasha Kempaiah, James B. Hittner, John Michael Ong'echa
Int J Biol Sci 2011; 7:1427-1442

MalariaWorldAn improved understanding of the etiological basis of suppression of erythropoietic responses in children with SMA may offer the much needed therapeutic alternatives for control of this global disease burden.

Letter: Host-mediated regulation of superinfection in malaria

June 7, 2011 - 13:39 -- Patrick Sampao
Silvia Portugal, Céline Carret, Maria M Mota, et al.
Nature Medicine Volume: 17, Pages 732–737 (2011)

Here we show in a mouse model that ongoing blood-stage infections, above a minimum threshold, impair the growth of subsequently inoculated sporozoites such that they become growth arrested in liver hepatocytes and fail to develop into blood-stage parasites.

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