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IFN-β

Beta Interferon Suppresses the Development of Experimental Cerebral Malaria

March 22, 2011 - 13:57 -- Patrick Sampao
Author(s): 
Craig N. Morrell, Kalyan Srivastava, AnneMarie Swaim, M. Teresa Lee, Jun Chen, Chandrashakaharam Nagineni, John J. Hooks, and Barbara Detrick
Reference: 
Infect. Immun., Apr 2011; 79: 1750 - 1758.

In this article, we report that IFN-β treatment leads to reduction of CXCL9 and ICAM-1 in the brain, reduction of T-cell CXCR3 expression, and downregulation of serum tumor necrosis factor alpha (TNF).

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