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adenovirus

Not Open Access | Review: Malaria vaccines: Focus on adenovirus based vectors

July 18, 2012 - 14:25 -- Patrick Sampao
Author(s): 
Nathaniel J. Schuldt, Andrea Amalfitano
Reference: 
Vaccine, Volume 30, Issue 35, 27 July 2012, Pages 5191-5198

This review will provide an update as to the current advancements in malaria vaccine development, with a focus on the use of adenovirus vectored malaria vaccines.

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Long-Term Humoral and Cellular Immune Responses Elicited by a Heterologous Plasmodium vivax Apical Membrane Antigen 1 Protein Prime/Adenovirus Boost Immunization Protocol

August 17, 2011 - 09:51 -- Patrick Sampao
Author(s): 
Leoneide Érica Maduro Bouillet, Mariana Oliveira Dias, Oscar Bruna-Romero, et al.
Reference: 
Infect. Immun., Sep 2011; 79: 3642 - 3652.

These results give further support to the need for preclinical studies of P. vivax vaccine candidate AMA-1 administered in prime/boost protocols that include recombinant proteins and adenoviral vectors.

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Adenovirus-vectored Plasmodium vivax ookinete surface protein, Pvs25, as a potential transmission-blocking vaccine

March 9, 2011 - 08:38 -- Patrick Sampao
Author(s): 
Takeshi Miyata., Tetsuya Harakuni., Takeshi Arakawa., et al.
Reference: 
Vaccine, Volume 29, Issue 15, 24 March 2011, Pages 2720-2726

This study, the first preclinical evaluation of adenovirus-vectored malaria OSPs, implicates a potential inclusion of malaria transmission-blocking vaccine antigens in viral vector systems.

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