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Open Access | Large-scale use of mosquito larval source management for malaria control in Africa: a cost analysis

November 9, 2011 - 13:04 -- Kabogo Ndegwa
Author(s): 
Worrall E, Fillinger U
Reference: 
Malaria Journal 2011, 10:338 (8 November 2011)

MalariaWorldCosts for LSM compare favourably with costs for IRS and LLINs, especially in areas with moderate and focal malaria transmission where mosquito larval habitats are accessible and well defined.

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An Integrated Chromosome Map of Microsatellite Markers and Inversion Breakpoints for an Asian Malaria Mosquito, Anopheles stephensi

October 27, 2011 - 14:22 -- Patrick Sampao
Author(s): 
Maryam Kamali, Maria V. Sharakhova, Elina Baricheva, Dmitrii Karagodin, Zhijian Tu and Igor V. Sharakhov
Reference: 
J Hered (November-December 2011) 102 (6): 719-726.

MalariaWorldThis study demonstrates that the chromosomal position of microsatellites may affect estimates of population genetic parameters and highlights the importance of developing physical maps for nonmodel organisms.

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The multifaceted mosquito anti-Plasmodium response

October 19, 2011 - 09:42 -- Patrick Sampao
Author(s): 
Eric Marois
Reference: 
Current Opinion in Microbiology, Volume 14, Issue 4, August 2011, Pages 429-435

MalariaWorldIn this brief review, we attempt to provide an integrated view of the challenges faced by the parasite to successfully invade its mosquito host, and discuss the possible intervention strategies that could exploit this knowledge for the fight against human malaria.

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Open Access | Field and Laboratory Evaluation of Bioefficacy of an Insect Growth Regulator (Dimilin) as a Larvicide against Mosquito and Housefly Larvae

September 20, 2011 - 13:53 -- Patrick Sampao
Author(s): 
Shandala Msangi, Ester Lyatuu, and Eliningaya J. Kweka
Reference: 
Journal of Tropical Medicine, Volume 2011 (2011)

Three formulations of Diflubenzuron were evaluated in this study: Dimilin, Wettable powder (25%), Dimilin granules (2%), and Dimilin tablets (2%).

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Open Access | Susceptibility of Anopheles stephensi to Plasmodium gallinaceum: A Trait of the Mosquito, the Parasite, and the Environment

June 21, 2011 - 07:27 -- Kabogo Ndegwa
Author(s): 
Jen C. C. Hume, Howard Hamilton III, Kevin L. Lee, Tovi Lehmann
Reference: 
PLoS ONE 6(6): e20156

The vector's genetics (heritability) comprised 67% of “vector susceptibility” measured by the prevalence of mosquitoes infected with P. gallinaceum oocysts, whereas the specific contribution of parasite genetics (heritability) to this trait was only 5%.

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Open Access | Commentary: Dissecting gene expression in mosquito

June 8, 2011 - 14:18 -- Patrick Sampao
Author(s): 
Rayna Stamboliyska and John Parsch
Reference: 
BMC Genomics 2011, 12:297, 7 June 2011

In addition to providing a valuable resource for the community of mosquito researchers, the study allows comparative transcriptomic studies of dipteran insects to be extended over 250 million years of evolution, since the divergence of A. gambiae and Drosophila melanogaster

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Open Access | The Puf-Family RNA-Binding Protein Puf2 Controls Sporozoite Conversion to Liver Stages in the Malaria Parasite

May 24, 2011 - 08:58 -- Kabogo Ndegwa
Author(s): 
Katja Müller, Kai Matuschewski, Olivier Silvie
Reference: 
PLoS ONE 6(5): e19860

Malaria is a vector-borne infectious disease caused by unicellular, obligate intracellular parasites of the genus Plasmodium.

Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito

May 17, 2011 - 15:12 -- Patrick Sampao
Author(s): 
Ludmilla Sologub, Andrea Kuehn, Selina Kern, Jude Przyborski, Rebecca Schillig, Gabriele Pradel
Reference: 
Cellular Microbiology, Volume 13, Issue 6, pages 897–912, June 2011

Via electron microscopy, we show that Plasmodium falciparum gametocytes exit the erythrocyte by an inside-out type of egress.

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Mosquito age and susceptibility to insecticides

April 26, 2011 - 14:03 -- Patrick Sampao
Author(s): 
Shavanthi Rajatileka, Joseph Burhani, Hilary Ranson
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 105, Issue 5, May 2011, Pages 247-253

This study investigated the impact of senescence and blood feeding on insecticide induced mortality in six different mosquito populations and found higher mortality after insecticide exposure in older mosquitoes in three populations of Aedes aegypti and two Anopheles gambiae populations.

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Open Access | Plasmodium Cysteine Repeat Modular Proteins 3 and 4 are essential for malaria parasite transmission from the mosquito to the host

April 5, 2011 - 08:12 -- Kabogo Ndegwa
Author(s): 
Douradinha B, Augustijn KD, Moore SG, Ramesar J, Mota MM, Waters AP, Janse CJ, Thompson J
Reference: 
Malaria Journal 2011, 10:71 (31 March 2011)

PCRMP3 and 4 play multiple roles during the Plasmodium life cycle; they are essential for the establishment of sporozoite infection in the mosquito salivary gland, and subsequently for development in hepatocytes.

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