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Falciparum

Proteomic Investigation of Falciparum and Vivax Malaria for Identification of Surrogate Protein Markers

August 22, 2012 - 06:47 -- Kabogo Ndegwa
Author(s): 
Sandipan Ray, Durairaj Renu, Sanjeeva Srivastava, et al.
Reference: 
PLoS ONE 7(8): e41751

MalariaWorldThis study was conducted to analyze alterations in the human serum proteome as a consequence of infection by malaria parasites Plasmodium falciparum and P. vivax to obtain mechanistic insights about disease pathogenesis, host immune response, and identification of potential protein markers.

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Remarkable stability in patterns of blood-stage gene expression during episodes of non-lethal Plasmodium yoelii malaria

August 8, 2012 - 07:11 -- Kabogo Ndegwa
Author(s): 
Cernetich-Ott A, Daly TM, Vaidya AB, Bergman LW, Burns JM
Reference: 
Malaria Journal 2012, 11:265 (6 August 2012)

MalariaWorldTaken together, these results indicate that 1) P. yoelii gene expression remains stable in the presence of a changing host environment, and 2) concurrent expression of a large number of the polymorphic yir and pyst-a genes, rather than differential expression in response to specific host factors, may in itself limit the effectiveness of host immune responses.

NOT Open Access | A Simple Dose Regimen of Artesunate and Amodiaquine Based on Arm Span- or Age Range for Childhood Falciparum Malaria: A Preliminary Evaluation

August 7, 2012 - 11:42 -- Kabogo Ndegwa
Author(s): 
Akintunde Sowunmi, Ibukun A. Akinrinola, Grace O. Gbotosho, Titilope M. Okuboyejo, and Christian T. Happi
Reference: 
J Trop Pediatr (2012) 58 (4): 263-268

MalariaWorldA dose regimen of artesunate and amodiaquine based on arm span- or age range (DRAAAS), derived from a study of 1674 children, was compared with standard dose regimen of the same drugs calculated according to body weight (SDRAA) in 68 malarious children.

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Not Open Access | Relative Contributions of Macrovascular and Microvascular Dysfunction to Disease Severity in Falciparum Malaria

August 1, 2012 - 14:08 -- Patrick Sampao
Author(s): 
Josh Hanson, Sophia W. K. Lam, Arjen M. Dondorp, et al.
Reference: 
J Infect Dis. (2012) 206 (4): 571-579

MalariaWorldVital organ dysfunction in severe malaria results primarily from sequestration of parasitized erythrocytes in the microvasculature rather than reduction in circulating blood volume and oxygen delivery.

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Comparison of CareStartTM HRP2/pLDH COMBO rapid malaria test with light microscopy in northwest Ethiopia

July 24, 2012 - 11:13 -- Kabogo Ndegwa
Author(s): 
Moges B, Amare B, Belyhun Y, Tekeste Z, Gizachew M, Workineh M, Gebrehiwot A, Woldeyohannes D, Mulu A, Kassu A
Reference: 
Malaria Journal 2012, 11:234 (20 July 2012)

MalariaWorldThe CareStartTM RDT test showed good sensitivity and specificity with an excellent agreement to the reference light microscopy.

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Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia

July 4, 2012 - 12:32 -- Patrick Sampao
Author(s): 
Siti Nurleila, Din Syafruddin, Iqbal R. F. Elyazar and J. Kevin Baird
Reference: 
Am J Trop Med Hyg 2012 87:41-49

MalariaWorldRecords of 3,449 patients admitted to Karitas Hospital at Waitabula in eastern Indonesia with microscopy-confirmed malaria through 2008 and 2009 were systematically reviewed.

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Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: a population-based study

April 27, 2012 - 12:37 -- Patrick Sampao
Author(s): 
R McGready, SJ Lee, FH Nosten, et al.
Reference: 
The Lancet Infectious Diseases, Volume 12, Issue 5, May 2012, Pages 388-396

MalariaWorldWe analysed all antenatal records of women in the first trimester of pregnancy attending Shoklo Malaria Research Unit antenatal clinics from May 12, 1986, to Oct 31, 2010.

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Open Access | Cytoadherence and virulence - the case of Plasmodium knowlesi malaria

February 8, 2012 - 08:52 -- Kabogo Ndegwa
Author(s): 
Fatih FA, Siner A, Ahmed A, Woon L, Craig AG, Singh B, Krishna S, Cox-Singh J
Reference: 
Malaria Journal 2012, 11:33 (3 February 2012)

MalariaWorldPlasmodium knowlesi infected erythrocytes from human subjects bind in a specific but variable manner to the inducible endothelial receptors ICAM-1 and VCAM.

Open Access | Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

October 20, 2011 - 08:54 -- Kabogo Ndegwa
Author(s): 
Panda AK, Panda SK, Sahu AN, Tripathy R, Ravindran B, Das BK
Reference: 
Malaria Journal 2011, 10:309 (19 October 2011)

MalariaWorldResults of the current study indicate that blood group 'O' is associated with reduced and 'B' blood group with increased risk of development of severe malaria in Odisha, India.

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CLOSED: Job: Post-Doctoral Position to study the effect of low power microwaves on Plasmodium falciparum

October 13, 2011 - 19:06 -- Ingeborg van Schayk
MalariaWorld
A post-doctoral position is available in the Dept. of Medicine, Penn State Univ. College of Medicine (USA) to work on a new research effort sponsored by the Bill and Melinda Gates Foundation.

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